极速11选5

【ZHONGGUOKEXUEBAO】ZKSCAN3KEYANHUANRENGANXIBAOSHUAILAO

  ZKSCAN3SHIJUYOUSCANJIEGOUYUDEXINZHIDANBAIJIAZUCHENGYUANZHIYI,CENGBEIBAODAOZUOWEIZHUANLUDIAOJIEYINZIYIZHIZISHIXIANGGUANJIYINDEBIAODA。RANERMUQIANGUOJISHANGGUANYUZKSCAN3DEYANJIUZHUYAOJIYUZHONGLIUXIBAOXIJIMOSHIDONGWU,QIZAIZHENGCHANGRENLEIGANXIBAODENGERBEITIXIBAOZHONGDESHENGWUXUEGONGNENGSHANGBUMINGQUE。

  5月19日,中国科学院动物研究所曲静研究组、刘光慧研究组及中国科学院北京基因组研究所张维绮研究组合作,在Nucleic Acids Research杂志在线发表最新研究成果。该研究首次报道ZKSCAN3通过自噬非依赖性的方式延缓人干细胞衰老。机制方面,ZKSCAN3能通过稳固细胞核膜蛋白与异染色质的相互作用,从而增强基因组稳定性并抑制重复元件表达。

  ZAIGAIXIANGYANJIUZHONG,YANJIURENYUANSHOUXIANFAXIANZKSCAN3ZAIRENLEIZAOSHUAIZHENGJIANCHONGZHIGANXIBAO、FUZHIXINGSHUAILAOJIANCHONGZHIGANXIBAO,YIJILAONIANGETIFENLIDEYUANDAIJIANCHONGZHIGANXIBAOZHONGJUNCHENGXIANCHUXIADIAOBIAODA,ANSHIZHEZKSCAN3YUSHUAILAODIAOKONGDEQIANZAILIANXI。JINERLIYONGCRISPR/Cas9JIEDAODEJIYINBIANJIJISHUHEGANXIBAODINGXIANGYOUDAOFENHUAJISHU,YANJIURENYUANSHOUCIHUODELEBAXIANGQIAOCHUZKSCAN3DERENPEITAIGANXIBAOHEJIANCHONGZHIGANXIBAO。JINGUANZKSCAN3DEQUESHIBUYINGXIANGRENPEITAIGANXIBAODEZIWOGENGXINHEFENHUA,DANZKSCAN3QIAOCHUDERENJIANCHONGZHIGANXIBAOZEBIAOXIANWEIJIASUSHUAILAODEBIAOXING。

  YANJIURENYUANJINYIBUTONGGUOZHENGHEXIANGHUZUOYONGDANBAIZHIPU、RANSEZHIMIANYIGONGCHENDIANCEXU、RANSEZHIKEJIXINGCEXU、DNAXIANPIAOLINGJIAJIZHUANYIMEIHUZUOCEXUJIRNACEXUDENGDUOCENGCIZUXUEFENXI,FAXIANZKSCAN3NENGYUHEMODANBAIHEYIRANSEZHIDANBAIXIANGHUZUOYONG。ZKSCAN3DEQUESHIDAOZHIRENJIANCHONGZHIGANXIBAOZHONGHEMODANBAITONGJIYINZUXIANGHUZUOYONGJIANRUO、YIRANSEZHIDIUSHI、JIYINZUZHONGFUYUANJIANZHUANLUSHUIPINGSHENGGAO,ZUIZHONGYOUFARENJIANCHONGZHIGANXIBAOSHUAILAO。ZHIDEZHUYIDESHI,GUOBIAODAZKSCAN3HUOTONGGUOCRISPRaXITONGJIHUONEIYUANZKSCAN3BIAODAJUNKEYANHUANRENJIANCHONGZHIGANXIBAOSHUAILAO。

极速11选5  GAIYANJIUSHOUCIJIESHILEZKSCAN3ZUOWEIBIAOGUANDIAOKONGYINZI,DIAOKONGRENGANXIBAOWENTAIBINGYIZHIQISHUAILAODEXINGONGNENGYUXINJIZHI。ZHEIYIFAXIANTUOZHANLERENMENDUIXINZHIDANBAIJIAZUXINGONGNENGDERENZHI,JIASHENLEDUISHUAILAOBIAOGUANYICHUANJIZHIDELIJIE,BINGWEIYANHUANGANXIBAOSHUAILAO、FANGZHISHUAILAOXIANGGUANJIBINGTIGONGLEZHONGYAODEXIANSUOHESILU。

  XIANGGUANLUNWENXINXI:https://doi.org/10.1093/nar/gkaa425

LAIYUAN:ZHONGGUOKEXUEBAO

关于我们
联系我们
地  址:北京市朝阳区北辰西路1号院5号
邮  编:100101
电子邮件:ioz@ioz.meiyingcn.com
电  话:+86-10-64807098
传  真:+86-10-64807099
友情链接